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Genes that overlap with segmental duplication regions and/or are flagged by repeatMasker are masked in this matrix

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Hello,

I have a question regarding your DepMap Public 24Q2 dataset, specifically about the file OmicsAbsoluteCNGene.csv.

You mentioned the following:

“Genes that overlap with segmental duplication regions and/or are flagged by repeatMasker are masked in this matrix.”

However, upon reviewing some of the masked genes (such as RPL10), I found that they do not appear to meet this criterion. I would like to understand why these genes are absent in OmicsAbsoluteCNGene.csv.

Additionally, I examined some genes that are present (such as RPS9) and noticed they have a significant amount of repeatMasker overlap. I am curious to know why they remain in the dataset given your filtering criteria.

I look forward to your response.

Thank you very much.

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