Hi, I have a simple question about the results after drug screening and CRISPR screening.
TL;DR Can the values in those screenings be considered in the same context?
To my knowledge, the CRISPRGeneEffect.csv contains the cell viability value after CRISPR screening, and Repurposing_Public_24Q2_Extended_Primary_Data_Matrix.csv in the PRISM dataset represents the Log2-fold-change viability values (LFC_cb) after drug screening.
I wonder whether they mean the same context (i.e., cell viability) and can be used as the same-level data for the machine learning methods.
In addition, the values in those files seem to have a similar range: about -1.67 ~ 4.85 and -26.389 ~ 8.07, respectively. If I compare them, does the lower value mean a stronger effect on the cell line?
Thank you for reading this question.
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