Hi everyone! I’m an undergraduate doing research based on gene expression and CRISPR gene effect data in Depmap. When I combine the expression and gene effect data together, I found various genes that are zero expressed in most tumor cell lines, but have a wide range of gene effect. For example, gene USP17L10 is not expressed in most tumor cell lines, but have a gene effect range from -1 to 0.6. How can we explain this? Thank you ~
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