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Multiple SMILES in secondary-screen-dose-response-curve-parameters.csv

Hello, I hope this message finds you well. I am currently working with the dataset in the file secondary-screen-dose-response-curve-parameters.csv and noticed that the “smiles” column contains...

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Availability of of RNA-seq bigwig files

Hello, I am looking for RNA-seq genome-wide coverage data in bigwig format (instead of table with expression per gene). Is this level of data available? Or a level of data that could be converted to...

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Normalization -TMM

Hi I want to understand that if I have to do TMM normalization rather than using TPM as TPM is not considered a very good parameter to compare across different samples. Which file with Raw reads would...

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Negative goodness of fit

Dear DepMap team, Why some r2 values in the Prism secondary-screen-dose-response-curve-parameters.csv file are negative? Isn’t r2 bounded between 0 and 1? Thanks 1 post - 1 participant Read full topic

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Non-breaking space in Model.csv current version (2024Q4)

Hi - Minor but I hit a potential problem using the current (2024Q4) version of Model.csv. For the entry for model ID ACH-000938, for the field ModelSubtypeFeatures, it contains “DUX4” and then some...

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error in custom analysis

I’m trying to compare the CRISPR dependencies of one cell line vs two other cell lines. It returns an unexpected error. 2 posts - 2 participants Read full topic

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